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[与流感相关的急性肌炎]

[Acute myositis associated with influenza].

作者信息

Noma Seiji

机构信息

Noma Children' s Clinic.

出版信息

Nihon Rinsho. 2006 Oct;64(10):1921-3.

Abstract

Benign acute myositis associated with influenza is reported from all over the world. The characteristics of this disorder is calf pain and difficulty walking during a viral illness (3-8 days) and creatine kinase levels are mildly or moderately elevated. Recovery occurred within 1 week. Midchildhood (mean age: 6-8 years) is most commonly affected and boys are more commonly than girls and its ratio is 2.4 : 1 by Shimizu in Japan (1993). Elderly patients are also reported. Viral studies show that influenza B is more commonly than influenza A and the ratio is 6 : 1 by Hu in Taiwan (2004), 2.4 : 1 by Shimizu in Japan (1993). Muscle histology revealed isolated segmental muscle degeneration and necrosis without frank myositis. A direct role of influenza virus in its genesis is not clear. An age-related response and occurrence primarily on boys may reflect a genetic predisposition.

摘要

世界各地均有关于与流感相关的良性急性肌炎的报道。这种疾病的特征是在病毒感染期间(3 - 8天)出现小腿疼痛和行走困难,肌酸激酶水平轻度或中度升高。1周内即可康复。儿童中期(平均年龄:6 - 8岁)最常受到影响,男孩比女孩更常见,日本的清水(1993年)报道其比例为2.4 : 1。也有老年患者的报道。病毒学研究表明,乙型流感比甲型流感更常见,台湾的胡(2004年)报道其比例为6 : 1,日本的清水(1993年)报道为2.4 : 1。肌肉组织学显示为孤立的节段性肌肉变性和坏死,无明显肌炎。流感病毒在其发病机制中的直接作用尚不清楚。与年龄相关的反应以及主要发生在男孩身上可能反映了一种遗传易感性。

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