Delavar Motahare A, Ebrahimi Hamidreza K, Borhani Nafise, Karimian Pegah, Ehsanipour Fahimeh, Jafarnejad Shabahang, Esmaeilian Somayeh
Department of Paediatrics, School of Medicine, Iran University of Medical Sciences, Ali Asghar Children's Hospital, Tehran, Iran.
Department of Emergency Medicine, School of Medicine, Iran University of Medical Sciences, Ali Asghar Children Hospital, Tehran, Iran.
J Family Med Prim Care. 2022 Jun;11(6):2744-2749. doi: 10.4103/jfmpc.jfmpc_1940_21. Epub 2022 Jun 30.
Influenza-related viral myositis is observed mostly in children with influenza, and the disease is more common in influenza type B. The aim of the present study was to evaluate the prevalence, and clinical and laboratory features of acute viral myositis in children with influenza in 2019 and 2020.
This retrospective cross-sectional study was performed in Ali Asghar Hospital, from December 2019 to February 2020. Children aged 2-14 years with symptoms of acute onset of fever, along with the symptoms of influenza with or without muscle pain who referred to the emergency department of Hazrat Ali Asghar Children's Hospital, were included in the study. The data were collected and analyzed by Statistical Package for the Social Sciences (SPSS) version 22.
Out of the 105 participants in this study, 62 (59%) were male and the rest were female. The average age of the patients was 5.34 years (SD = 2.63). Clinical signs of lower limb pain, myalgia, lameness, weakness, and lethargy were significantly more common in patients with myositis (-value < 0.05). examination demonstrated that creatine phosphokinase (CPK), aspartate aminotransferase (AST), and aAlanine aminotransferease (ALT) levels were significantly higher in patients with myositis.
Based on the present results, the clinical symptoms in patients are quite clear, and based on the symptoms, it is possible to diagnose and treat myositis without relying on laboratory findings; due to the self-limitation of this complication and lack of the need for complex treatments in case of early diagnosis, physicians can diagnose and treat many cases, depending on the clinical symptoms and the accuracy of the examination.
流感相关病毒性肌炎多见于患流感的儿童，且该疾病在乙型流感中更为常见。本研究的目的是评估2019年和2020年患流感儿童急性病毒性肌炎的患病率、临床及实验室特征。
本回顾性横断面研究于2019年12月至2020年2月在阿里·阿斯加尔医院进行。纳入年龄在2至14岁、有急性发热症状以及有或无肌肉疼痛的流感症状并前往阿里·阿斯加尔儿童医院急诊科就诊的儿童。数据采用社会科学统计软件包（SPSS）22版进行收集和分析。
本研究的105名参与者中，62名（59%）为男性，其余为女性。患者的平均年龄为5.34岁（标准差=2.63）。肌炎患者下肢疼痛、肌痛、跛行、无力和嗜睡等临床体征明显更为常见（P值<0.05）。检查显示，肌炎患者的肌酸磷酸激酶（CPK）、天冬氨酸转氨酶（AST）和丙氨酸转氨酶（ALT）水平明显更高。
基于目前的结果，患者的临床症状相当明确，基于这些症状，无需依赖实验室检查结果即可诊断和治疗肌炎；由于该并发症具有自限性且早期诊断时无需复杂治疗，医生可根据临床症状和检查准确性诊断和治疗许多病例。
