Wichowicz Hubert, Gasecki Dariusz, Landowski Jerzy, Lass Piotr, Nyka Walenty M, Kozera Grzegorz
Klinika Chorób Psychicznych i Zaburzeń Nerwicowych Katedry Chorób Psychicznych AM w Gdańsku.
Psychiatr Pol. 2006 May-Jun;40(3):539-50.
The aim of this paper was to assess the risk for depression in a 6-month-long post stroke follow up period as related to the stroke variables (i.e. stroke localisation, haemodynamic parameters).
The stroke localisation was determined with CT and/or MRI. Subsequently all the examined individuals underwent SPECT examination. The follow up examinations were performed by the consultant psychiatrist in 6, 12 and 24 weeks subsequent to the stroke episode. The depressive episode diagnosis was established on the basis of ICD-10 diagnostic criteria.
Only right-handed patients (43 men aged 57.3 +/- 11.6 and 17 women aged 62.5 +/- 14.4) with unilateral brain lesion were examined. 23 subjects (38%) developed depression in the follow-up period. 5 women (29%) and 18 men (ca. 42%) developed a depressive episode. Only one of the observed depressive episodes met ICD-10 criteria for severe depressive episode. 10 patients suffered from moderate depressive episode and 12 subjects exhibited a mild depressive episode.
The results obtained with CT and/or MRI techniques revealed no correlation between the post-stroke depression and stroke lateralisation. However the localisation of the deep brain functional abnormalities revealed with SPECT correlated with the occurrence of the affective disorders as related to the asymmetry in regional blood flow measures.
本文旨在评估在中风后6个月的随访期内，与中风变量（即中风部位、血流动力学参数）相关的抑郁风险。
通过CT和/或MRI确定中风部位。随后，所有接受检查的个体均接受SPECT检查。随访检查由顾问精神科医生在中风发作后的6周、12周和24周进行。抑郁发作的诊断依据ICD - 10诊断标准确定。
仅对单侧脑损伤的右利手患者（43名年龄为57.3 +/- 11.6岁的男性和17名年龄为62.5 +/- 14.4岁的女性）进行了检查。23名受试者（38%）在随访期内出现抑郁。5名女性（29%）和18名男性（约42%）出现抑郁发作。观察到的抑郁发作中只有一例符合ICD - 10中重度抑郁发作的标准。10名患者患有中度抑郁发作，12名受试者表现为轻度抑郁发作。
CT和/或MRI技术获得的结果显示，中风后抑郁与中风侧别之间无相关性。然而，SPECT显示的深部脑功能异常部位与情感障碍的发生相关，这与区域血流测量的不对称有关。
