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用于神经保护的血流逆转经颈颈动脉支架置入术:技术、结果、优势及局限性

Transcervical carotid stenting with flow reversal for neuroprotection: technique, results, advantages, and limitations.

作者信息

Pipinos Iraklis I, Bruzoni Matias, Johanning Jason M, Matthew Longo G, Lynch Thomas G

机构信息

Department of Surgery, University of Nebraska Medical Center, Omaha, NE 68198-3280, USA.

出版信息

Vascular. 2006 Sep-Oct;14(5):245-55. doi: 10.2310/6670.2006.00050.

Abstract

Carotid angioplasty and stenting are progressively earning a role as a less invasive alternative in the treatment of carotid occlusive disease. The most common approach for carotid artery stenting involves transfemoral access and use of a filter or balloon device for neuroprotection. This approach has limitations related to both the site of access and the method of neuroprotection. Specifically, an aortoiliac segment with advanced occlusive or aneurysmal disease or an anatomically unfavorable or atheromatous arch and arch branches can significantly limit the safety of the retrograde transfemoral pathway to the carotid bifurcation. Additionally, data provided by the use of transcranial Doppler monitoring and diffusion-weighted magnetic resonance imaging in patients undergoing filter- or balloon-protected carotid artery stenting demonstrate that currently available devices are associated with a considerable incidence of cerebral embolization. To address these limitations, we, along with others, have employed a direct transcervical approach for carotid artery stenting that incorporates the principle of flow reversal for neuroprotection. The technique bypasses all of the anatomic limitations of transfemoral access and simplifies the application of flow reversal, which is one of the safest neuroprotection techniques. The purpose of this review is to describe our method of transcervical carotid artery stenting, review the accumulating outcomes data, and discuss the clinical advantages of and indications for this increasingly popular technique.

摘要

颈动脉血管成形术和支架置入术正逐渐成为治疗颈动脉闭塞性疾病的一种侵入性较小的替代方法。颈动脉支架置入术最常见的方法是经股动脉入路,并使用滤器或球囊装置进行神经保护。这种方法在入路部位和神经保护方法方面都存在局限性。具体而言,患有严重闭塞性或动脉瘤性疾病的腹主动脉髂动脉段,或解剖结构不利或动脉粥样硬化的主动脉弓及其分支,会显著限制逆行经股动脉途径至颈动脉分叉处的安全性。此外,在接受滤器或球囊保护的颈动脉支架置入术的患者中,经颅多普勒监测和弥散加权磁共振成像提供的数据表明,目前可用的装置与相当高的脑栓塞发生率相关。为了解决这些局限性,我们和其他人采用了一种直接经颈入路的颈动脉支架置入术,该方法纳入了血流逆转原理以进行神经保护。该技术绕过了经股动脉入路的所有解剖学限制,并简化了血流逆转的应用,血流逆转是最安全的神经保护技术之一。本综述的目的是描述我们的经颈颈动脉支架置入术方法,回顾积累的结果数据,并讨论这种日益流行的技术的临床优势和适应证。

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