Van der Molen A J, Veldkamp W J H, Geleijns J
Department of Radiology C-2S, Leiden University Medical Center, Albinusdreef 2, NL-2333 ZA Leiden, The Netherlands.
Br J Radiol. 2007 Apr;80(952):248-55. doi: 10.1259/bjr/52356535. Epub 2006 Oct 12.
The aim of the study was to investigate achievable dose levels in 16-slice CT by evaluating CT dose indices (CTDI) and effective doses of dose-optimized protocols compared with 4-slice dose surveys. Normalized CTDI free in air and in 16 cm and 32 cm diameter phantoms were measured on four different 16-slice CT scanners in the Netherlands. All collimation and tube potential settings were analysed. Volume CTDI was calculated for adult protocols for brain, chest, pulmonary angiography (CTPA), abdomen and biphasic liver CT. Effective doses were calculated first using volume CTDI with conversion factors and second from CTDIair values using the ImPACT dose calculator. Average results of the 16-slice scanners were correlated to results of dose surveys with predominantly 4-slice scanners. Statistical analysis was done with Student t-tests with a Bonferroni correction; therefore p < 0.017 was significant. The results of CTDIair and weighted CTDI were documented for all scanners. Effective doses averaged over four scanners for brain, chest, CTPA, abdomen and biphasic liver protocols were 1.9+/-0.4, 3.8+/-0.4, 3.0+/-0.2, 7.2+/-0.9 and 10.2+/-1.3 mSv, respectively. Compared with dose surveys achievable effective doses were equal (p = 0.069) to significantly lower (p < 0.017) for chest and abdomen protocols. For 16-slice spiral brain CT there was a trend of equal doses compared with sequential brain CT in the dose surveys. Thus, with dose-optimized protocols 16-slice CT can achieve equal to lower effective doses in examinations of the chest and abdomen compared with 4-slice CT, while doses can remain stable in the brain.
本研究的目的是通过评估CT剂量指数(CTDI)以及与4层CT剂量调查相比剂量优化方案的有效剂量,来研究16层CT可达到的剂量水平。在荷兰的四台不同的16层CT扫描仪上测量了空气中、直径16 cm和32 cm模体中的归一化CTDI。分析了所有的准直和管电压设置。计算了成人脑部、胸部、肺血管造影(CTPA)、腹部和肝脏双期CT方案的容积CTDI。首先使用容积CTDI和转换系数计算有效剂量,其次使用ImPACT剂量计算器根据空气CTDI值计算有效剂量。16层扫描仪的平均结果与主要使用4层扫描仪的剂量调查结果相关。采用具有Bonferroni校正的Student t检验进行统计分析;因此,p < 0.017具有显著性。记录了所有扫描仪的空气CTDI和加权CTDI结果。四台扫描仪上脑部、胸部、CTPA、腹部和肝脏双期CT方案的平均有效剂量分别为1.9±0.4、3.8±0.4、3.0±0.2、7.2±0.9和10.2±1.3 mSv。与剂量调查相比,胸部和腹部方案的可达到有效剂量相等(p = 0.069)至显著更低(p < 0.017)。对于16层螺旋脑部CT,与剂量调查中的序列脑部CT相比,有剂量相等的趋势。因此,与4层CT相比,采用剂量优化方案的16层CT在胸部和腹部检查中可达到相等至更低的有效剂量,而脑部剂量可保持稳定。