Guevara-Gutiérrez E, Tlacuilo-Parra A, Minjares-Padilla L M
Department of Dermatology, Instituto Dermatológico de Jalisco, Secretaria de Salud, Jalisco, México.
J Clin Rheumatol. 2001 Dec;7(6):401-2. doi: 10.1097/00124743-200112000-00010.
Incisional biopsy of labial salivary glands has been a valuable technique for diagnosis of Sjögren's syndrome. This report describes a new technique using punch biopsies that requires fewer resources and appears to be equally effective. Fifty patients evaluated by punch biopsy all yielded adequate pieces averaging 6 glands per specimen. Two patients had transient numbness of the lip. There were no other complications. Classical findings of Sjögren's histopathology were demonstrable with these specimens. This technique is safe, less expensive, and is proposed as a reliable alternative to incisional biopsy.
唇唾液腺切开活检一直是诊断干燥综合征的一项重要技术。本报告描述了一种使用打孔活检的新技术，该技术所需资源更少，且似乎同样有效。通过打孔活检评估的50例患者均获得了足够的组织块，每个标本平均有6个腺体。2例患者出现唇部短暂麻木。无其他并发症。这些标本可显示干燥综合征的典型组织病理学表现。该技术安全、成本较低，被认为是切开活检的可靠替代方法。
