Abelardo E, Jaramillo M, Sheffield E, Tierney P
Department of ENT, Southmead Hospital, Bristol, UK.
J Laryngol Otol. 2007 Mar;121(3):268-70. doi: 10.1017/S0022215106003264. Epub 2006 Oct 2.
We report the case of a 59-year-old man with a two-month history of a fast-growing, left-sided neck mass and a 5 mm nodule over a thyroid mass at the site of fine needle aspiration cytology performed four weeks earlier. Histopathological studies confirmed anaplastic carcinoma of the thyroid and cutaneous needle track seeding of the primary tumour. The patient succumbed to extensive disease 10 weeks after initial diagnosis. To our knowledge, this is a rare report of implantation of anaplastic thyroid carcinoma along the track of fine needle aspiration. Some factors involved in needle track seeding are: needle size; number of passes; withdrawing the needle without releasing suction; injecting the tumour at time of biopsy; and inherent characteristics of the lesion (e.g. number of cells dislodged, adhesiveness of cells, amount of stroma present, enzymes released and immunologic characteristics).
我们报告了一例59岁男性患者,其左侧颈部有一个生长迅速的肿块,病史两个月,在四周前进行细针穿刺细胞学检查的甲状腺肿块部位有一个5毫米的结节。组织病理学研究证实为甲状腺间变性癌,且原发肿瘤沿皮肤穿刺针道播散。患者在初次诊断10周后死于广泛转移。据我们所知,这是一例罕见的沿细针穿刺针道种植甲状腺间变性癌的报告。针道种植涉及的一些因素包括:针的大小;穿刺次数;不松开负压而拔出针;活检时向肿瘤内注射;以及病变的固有特征(例如脱落的细胞数量、细胞的黏附性、间质的数量、释放的酶和免疫特征)。