Transfection systems for animal models of malaria.
作者信息
Tomas A M, van der Wel A M, Thomas A W, Janse C J, Waters A P
机构信息
Instituto de Biologia Molecular e Celular, Porto University, R. Campo Alegre, 823, 4150 Porto, Portugal.
出版信息
Parasitol Today. 1998 Dec;14(6):245-9. doi: 10.1016/s0169-4758(98)01248-4.
Abstract
Transfection of malaria parasites is a rapidly emerging technology that offers great promise for the investigation of many aspects of infection. Animal models of malaria have always played an important role in the investigation of the disease. In this article, two of the Dutch groups that have been involved in combining transfection with animal models describe the relevant techniques and recent vector developments for the expression of transgenes, giving examples of their application.
摘要
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