Liston D R, Johnson P J
Department of Microbiology and Immunology, Molecular Biology Institute, University of California, Los Angeles School of Medicine, Los Angeles, CA 90095-1747, USA.
Parasitol Today. 1998 Jul;14(7):261-5. doi: 10.1016/s0169-4758(98)01264-2.
Since the cloning of the first gene from the flagellated, parasitic protist Trichomonas vaginalis in 1990, at least a partial sequence has been obtained from over 100 genes. Molecular and biochemical analyses using these genes have enhanced our understanding of metabolism, organelle biogenesis, drug susceptibility, phylogeny and basic properties of transcription in trichomonads. Here, David Liston and Patricia Johnson discuss the available data on the regulation of transcription of protein-coding genes in T. vaginalis.
自1990年从有鞭毛的寄生原生生物阴道毛滴虫中克隆出第一个基因以来，已经从100多个基因中获得了至少部分序列。利用这些基因进行的分子和生化分析，加深了我们对阴道毛滴虫的代谢、细胞器生物发生、药物敏感性、系统发育和转录基本特性的理解。在此，大卫·利斯顿和帕特里夏·约翰逊讨论了关于阴道毛滴虫蛋白质编码基因转录调控的现有数据。
