Hammond Alison
Rheumatology Department, Derbyshire Royal Infirmary, Derby.
Musculoskeletal Care. 2004;2(3):135-51. doi: 10.1002/msc.66.
This article considers the evidence for effectiveness and timing of rehabilitation for people with rheumatoid arthritis (RA). The Cochrane Library, DARE, Medline, Embase, CINAHL and AMED were searched to identify systematic reviews and randomized controlled trials evaluating rehabilitation interventions for people with rheumatoid arthritis. Many trials identified had methodological limitations (e.g. short follow-up periods, small sample sizes). Evidence to date is that symptomatic relief results from thermotherapy, laser therapy, acupuncture and assistive devices. In the short-term, comprehensive occupational therapy (in established rheumatoid arthritis), orthoses, and mind-body approaches can help maintain function. Over at least a one-year period, the following are effective in reducing pain and maintaining function: patient education and joint protection training using behavioural approaches; dynamic exercise therapy, hand exercises and hydrotherapy; and cognitive-behavioural therapy (in people with poorer psychological status). Many trials have recruited people with moderate to severe, established RA and relatively little is known about the long-term effectiveness of early rehabilitation, although this is becoming much more common in practice. Despite the increased availability of guidelines and systematic reviews, most conclude there is insufficient evidence for many areas of rheumatology rehabilitation. Further well-designed clinical trials are needed recruiting people with early disease using patient-centred outcomes.
本文探讨了类风湿关节炎(RA)患者康复治疗的有效性及时机的证据。检索了考克兰图书馆、DARE、医学索引数据库、荷兰医学文摘数据库、护理学与健康领域数据库及联合和补充医学数据库,以确定评估类风湿关节炎患者康复干预措施的系统评价和随机对照试验。所纳入的许多试验存在方法学局限性(如随访期短、样本量小)。目前的证据表明,热疗、激光治疗、针灸和辅助器械可缓解症状。短期内,综合职业疗法(针对确诊的类风湿关节炎患者)、矫形器和身心疗法有助于维持功能。至少在一年的时间里,以下方法在减轻疼痛和维持功能方面有效:采用行为方法进行患者教育和关节保护训练;动态运动疗法、手部运动和水疗;以及认知行为疗法(针对心理状态较差的患者)。许多试验纳入的是中度至重度确诊类风湿关节炎患者,对于早期康复的长期有效性了解相对较少,尽管在实际中这种情况正变得越来越普遍。尽管指南和系统评价越来越多,但大多数结论认为,在风湿病康复的许多领域,证据仍然不足。需要开展更多设计良好的临床试验,纳入早期疾病患者,并以患者为中心的结局指标进行评估。