[5-羟色胺和5-羟吲哚乙酸在胺前体摄取脱羧细胞瘤诊断中的应用]
[The application of 5-HT and 5-HIAA in the diagnosis of apudomas].
作者信息
Xu S H, Chen Y F, Chen H C
机构信息
Institute of Basic Medical Sciences, CAMS, Beijing.
出版信息
Zhonghua Nei Ke Za Zhi. 1990 Jul;29(7):428-31, 446.
5-HT apudomas are rare. In our country, so far there has been no detailed report about using whole blood 5-HT and urinary 5-HIAA in the diagnosis of apudomas. Measurement of whole blood 5-HT in 87 and urinary 5-HIAA in 44 apudoma patients has been carried out in our laboratory since 1980. The results showed that the values of whole blood 5-HT and urinary 5-HIAA were significantly higher in apudoma patients than those in non-apudoma, postoperative apudoma and normal groups. The value of whole blood 5-HT over 130 micrograms/ml and urinary 5-HIAA over 30 mg/24 h were preliminarily recommended as diagnostic for apudomas.
5-羟色胺瘤极为罕见。在我国，迄今尚无关于采用全血5-羟色胺及尿5-羟吲哚乙酸诊断胺前体摄取脱羧细胞瘤的详细报告。自1980年以来，我们实验室对87例胺前体摄取脱羧细胞瘤患者进行了全血5-羟色胺测定，对44例患者进行了尿5-羟吲哚乙酸测定。结果显示，胺前体摄取脱羧细胞瘤患者的全血5-羟色胺及尿5-羟吲哚乙酸值显著高于非胺前体摄取脱羧细胞瘤患者、胺前体摄取脱羧细胞瘤术后患者及正常组。初步建议将全血5-羟色胺值超过130微克/毫升及尿5-羟吲哚乙酸值超过30毫克/24小时作为胺前体摄取脱羧细胞瘤的诊断标准。
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