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[体外冲击波胆道碎石术中的期前收缩。其发生率及临床意义]

[Extrasystoles during extracorporeal biliary shockwave lithotripsy. Their incidence and clinical significance].

作者信息

Rambow A, Staritz M, Grosse A, Treese N, Mayer K, Meyer zum Büschenfelde K H

机构信息

I. Medizinische Klinik und Poliklinik, Universität Mainz.

出版信息

Dtsch Med Wochenschr. 1991 Feb 15;116(7):248-53. doi: 10.1055/s-2008-1063606.

Abstract

Incidence and clinical significance of cardiac side effects of extracorporeal shock-wave lithotripsy (ESWL) were prospectively analysed for 85 patients (26 men, 59 women; mean age 44 [17-81] years) with cholecystolithiasis (n = 70) or choledocholithiasis (n = 15). 24-hour ECG monitoring was undertaken on the day of treatment. Additionally, during ESWL cardiac rhythm and blood pressure were monitored. ESWL was performed with an electromagnetic lithotriptor under light anaesthesia with intravenous diazepam (10 mg) and pethidine (75-100 mg). There were no superventricular premature systoles in any of the patients during treatment. In 15 patients with occasional ventricular premature systoles (VPS) (6-81 per 23 hours) in the 24-hour ECG the number of VPS increased during the one-hour ESWL procedure significantly to 6-55 (P less than 0.05). 14 of these patients had an unremarkable cardiac history. Changing the lithotriptor coupling angle failed to suppress the VPS in only two patients. In these two it was necessary to trigger the shock wave with the ECG. Blood pressure rose markedly (up to 220 mm Hg systolic) during ESWL in only three patients, known hypertensives. But this rise was easily controlled with nifedipine, 10 mg sublingually. These data demonstrate that ESWL is a safe alternative to operative treatment, even in the presence of existing cardiac disease. Nonetheless, precautions should be taken in case there are complications.

摘要

对85例患有胆囊结石(n = 70)或胆总管结石(n = 15)的患者(26例男性,59例女性;平均年龄44 [17 - 81]岁),前瞻性分析了体外冲击波碎石术(ESWL)心脏副作用的发生率及临床意义。在治疗当天进行24小时心电图监测。此外,在ESWL期间监测心律和血压。使用电磁碎石机在静脉注射地西泮(10 mg)和哌替啶(75 - 100 mg)的轻度麻醉下进行ESWL。治疗期间所有患者均未出现室上性早搏。在24小时心电图检查中,15例患者偶尔出现室性早搏(VPS)(每23小时6 - 81次),在1小时的ESWL过程中,VPS数量显著增加至6 - 55次(P小于0.05)。其中14例患者既往心脏病史无异常。仅2例患者改变碎石机耦合角度未能抑制VPS。在这2例患者中,有必要通过心电图触发冲击波。仅3例已知高血压患者在ESWL期间血压显著升高(收缩压高达220 mmHg)。但舌下含服10 mg硝苯地平可轻松控制这种升高。这些数据表明,即使存在现有心脏病,ESWL也是手术治疗的安全替代方法。尽管如此,如有并发症应采取预防措施。

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