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[脊柱硬膜外脓肿。有限手术治疗联合持续冲洗引流]

[Spinal epidural empyema. Limited surgical treatment combined with continuous irrigation and drainage].

作者信息

Mauer U M, Kunz U

机构信息

Abteilung Neurochirurgie, Bundeswehrkrankenhaus, Oberer Eselsberg 40, 89070 Ulm, Germany.

出版信息

Unfallchirurg. 2007 Mar;110(3):250-4. doi: 10.1007/s00113-006-1178-2.

Abstract

Epidural empyema of the spinal column is a rare, but in some cases devastating, disease. Surgery can be excessive or very limited. We want to report our results of combined therapy of limited surgical treatment and continuous irrigation with antibiotic solution and drainage. In the last 5 years we have operated on 12 patients (7 female, 5 male, median age: 61.5 years, range: 22-89 years) with spinal epidural empyema. All surviving patients were evaluated after 3 months including MRI. Six infections were caused by injections, two by spontaneous discitis, two by chronic systemic infections, and in two patients the cause remained unknown. In every case we implanted two catheters, one for irrigation with antibiotic solution and one for drainage. On average the catheters were used for 3 days. For evacuation in seven patients interlaminar fenestration in one, two, or three levels was enough. Only in one patient was a laminectomy performed. Five patients recovered totally, three partially, one did not recover at all, and three died. The autopsy of two dead patients showed complete healing of the operated area; they died because of lethal infections in other parts of their body. In only one case did a reoperation have to be done. The cause was an additional subdural empyema. In spite of the limited surgical procedure without relevant operative morbidity the reported method is an effective and safe therapy.

摘要

脊柱硬膜外脓肿是一种罕见但在某些情况下具有毁灭性的疾病。手术治疗可能过度或非常有限。我们想报告我们采用有限手术治疗联合抗生素溶液持续冲洗及引流的治疗结果。在过去5年里,我们对12例脊柱硬膜外脓肿患者进行了手术(7例女性,5例男性,中位年龄:61.5岁,范围:22 - 89岁)。所有存活患者在3个月后包括通过磁共振成像(MRI)进行了评估。6例感染由注射引起,2例由自发性椎间盘炎引起,2例由慢性全身感染引起,2例患者病因不明。在每种情况下,我们都植入了两根导管,一根用于抗生素溶液冲洗,一根用于引流。导管平均使用3天。对于7例患者,在一个、两个或三个节段进行椎板间开窗减压就足够了。仅1例患者进行了椎板切除术。5例患者完全康复,3例部分康复,1例未康复,3例死亡。2例死亡患者的尸检显示手术区域完全愈合;他们因身体其他部位的致命感染而死亡。仅1例患者需要再次手术。原因是合并了硬膜下脓肿。尽管手术操作有限且无相关手术并发症,但所报道的方法是一种有效且安全的治疗方法。

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