Mukhida Karim, Asa Sylvia, Gentili Fred, Shannon Patrick
Division of Neurosurgery, University of Toronto and Toronto Western Hospital, Toronto, Ontario, Canada.
J Neurosurg. 2006 Oct;105(4):616-20. doi: 10.3171/jns.2006.105.4.616.
The authors describe a case of pituitary fossa ependymoma and discuss its immunohistochemical and ultrastructural characteristics. A 43-year-old man presented with decreased libido and panhypopituitarism. Magnetic resonance imaging demonstrated a well-demarcated enhancing lesion of the pituitary fossa that was completely resected via a transsphenoidal approach. Ependymomas rarely occur in the pituitary fossa, and have been reported in this location only three times in humans and once in a horse. This is the first study in which investigators examined the appearance of a pituitary ependymoma by using electron microscopy. Theories of the origin and treatment of these rare tumors are discussed as they relate to other articles on intracranial ependymomas.
作者描述了一例垂体窝室管膜瘤病例，并讨论了其免疫组织化学和超微结构特征。一名43岁男性出现性欲减退和全垂体功能减退。磁共振成像显示垂体窝有一个边界清晰的强化病变，通过经蝶窦入路将其完全切除。室管膜瘤很少发生在垂体窝，在该部位仅在人类中有三次报道，在一匹马中有一次报道。这是第一项研究，研究人员通过电子显微镜检查了垂体室管膜瘤的外观。这些罕见肿瘤的起源和治疗理论与其他关于颅内室管膜瘤的文章相关，文中对此进行了讨论。
