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[神经肽血管加压素、催产素和加压催产素对软体动物神经元膜电控离子通道的突触外效应]

[The extrasynaptic effect of the neuropeptides vasopressin, oxytocin and vasotocin on the electrically controlled ion channels of the membrane in mollusk neurons].

作者信息

Artem'ev I Iu, Darinskiĭ Iu A

出版信息

Neirofiziologiia. 1990;22(4):526-33.

PMID:1704490
Abstract

Extrasynaptic effects of vasopressin, oxytocin, vasotocin on the membrane electrosensitive ionic channels were studied in model experiments using isolated somata from the CNS of mollusc Lymnaea stagnalis. The neuropeptide in concentrations of 1.10(-16)-1.10(-6) mol/l either blocked or induced biphasic dose-dependent effect on amplitudes of the membrane ionic currents.

摘要

利用从椎实螺中枢神经系统分离出的胞体进行模型实验,研究了血管加压素、催产素、加压催产素对膜电敏感离子通道的突触外效应。浓度为1.10(-16)-1.10(-6)mol/l的神经肽对膜离子电流幅度要么产生阻断作用,要么诱导双相剂量依赖性效应。

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