Sugino Ryuichi P, Innan Hideki
University of Texas Health Science Center at Houston School of Public Health, Human Genetics Center, 1200 Hermann Pressler, Houston, TX 77030, USA.
Trends Genet. 2006 Dec;22(12):642-4. doi: 10.1016/j.tig.2006.09.014. Epub 2006 Oct 11.
The duration of concerted evolution after gene duplication is highly variable across genes. To identify the cause of the variation, we analyzed of duplicated genes in yeast that originate from a whole genome duplication event. There appears to be a strong positive correlation between the duration of concerted evolution and the gene expression level. This observation can be explained by selection favoring more of the same product, which could enhance concerted evolution in dosage-sensitive genes.
基因复制后协同进化的持续时间在不同基因间差异很大。为了确定这种变异的原因，我们分析了酵母中源自全基因组复制事件的重复基因。协同进化的持续时间与基因表达水平之间似乎存在很强的正相关。这一观察结果可以用有利于产生更多相同产物的选择来解释，这可能会增强剂量敏感基因中的协同进化。
