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脑钠肽作为β地中海贫血心肌铁负荷的标志物

Brain natriuretic peptide as marker of myocardial iron load in beta-thalassemia.

作者信息

Nikolidakis Savvas, Flessa Constantina, Nikolaou Nikolaos, Gotsis Efstathios D, Koutouzis Michael, Polyhronaki Eleni, Vrettou Eleni, Kyriakides Zenon S

出版信息

Int J Cardiol. 2007 Jun 12;118(3):408-9. doi: 10.1016/j.ijcard.2006.07.052. Epub 2006 Oct 12.

DOI:10.1016/j.ijcard.2006.07.052
PMID:17045671
Abstract

Cardiomyopathy due to iron overload represents a frequent life-limiting complication in patients with beta-thalassemia major. We have conducted a study which proved that brain natriuretic peptide plasma levels have high sensitivity and negative predictive value in detecting cardiac hemosiderosis.

摘要

铁过载所致的心肌病是重型β地中海贫血患者常见的危及生命的并发症。我们开展了一项研究，结果证明血浆脑钠肽水平在检测心脏铁沉积方面具有高敏感性和阴性预测价值。

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