一种使用同步辐射的X射线微探针设备。

An X-ray microprobe facility using synchrotron radiation.

作者信息

Gordon B M, Jones K W, Hanson A L, Pounds J G, Rivers M L, Spanne P, Sutton S R

机构信息

Department of Applied Science, Brookhaven National Laboratory, Upton, NY 11973.

出版信息

Biol Trace Elem Res. 1990 Jul-Dec;26-27:133-41. doi: 10.1007/BF02992666.

DOI:10.1007/BF02992666

PMID:1704712

Abstract

An X-ray microprobe for trace elemental analysis at micrometer spatial resolutions, using synchrotron radiation (SR), is under development. The facility consists of two beamlines, one including a 1:1 focusing mirror and the other an 8:1 ellipsoidal mirror. At present, "white light" is used for excitation of the characteristic X-ray fluorescence lines. Sensitivities in thin biological samples are in the range of 2-20 fg in 100 microns2 areas in 5 min irradiation times. Scanning techniques, as well as microtomography and chemical speciation, are discussed. Application to a specific biomedical study is included.

摘要

一种利用同步辐射（SR）进行微米级空间分辨率痕量元素分析的X射线微探针正在研发中。该设施由两条光束线组成，一条包括1:1聚焦镜，另一条包括8:1椭球镜。目前，“白光”用于激发特征X射线荧光线。在5分钟的辐照时间内，薄生物样品中100微米²区域的灵敏度在2-20飞克范围内。讨论了扫描技术以及显微断层扫描和化学形态分析。还包括在一项特定生物医学研究中的应用。