Behne D, Scheid S, Hilmert H, Gessner H, Gawlik D, Kyriakopoulos A
Hahn-Meitner-Institut Berlin, FRG.
Biol Trace Elem Res. 1990 Jul-Dec;26-27:439-47. doi: 10.1007/BF02992699.
In several studies on rats, the metabolism of selenium was investigated. The quantitative determination of the element was carried out by instrumental neutron activation analysis. For in vivo tracer experiments, 75Se-labeled selenium compounds were used. In addition to these methods, procedures for the measurement of the selenoenzyme glutathione peroxidase, and for the investigation of other selenoproteins, were applied. In this way, information on the specific pools and sites of action of the element, on biologically important selenoproteins and the regulation of the selenium metabolism, was obtained.
在几项针对大鼠的研究中，对硒的代谢进行了调查。该元素的定量测定通过仪器中子活化分析进行。对于体内示踪实验，使用了75Se标记的硒化合物。除了这些方法外，还应用了测量硒酶谷胱甘肽过氧化物酶以及研究其他硒蛋白的程序。通过这种方式，获得了关于该元素的特定储存库和作用位点、具有生物学重要性的硒蛋白以及硒代谢调节的信息。
