Behne D, Höfer T, von Berswordt-Wallrabe R, Elger W
J Nutr. 1982 Sep;112(9):1682-7. doi: 10.1093/jn/112.9.1682.
In male rats, fed for 10 weeks on a Torula yeast-based, low selenium and low vitamin E diet, the selenium level and the glutathione peroxidase activity in the blood and in several tissues decreased by 50 to 98% compared with animals that received the same basal diet supplemented with 0.25 mg Se/kg sodium selenite. In the testes, however, the selenium content did not differ from that of the control animals. Despite the low selenium levels in the extragonadal tissues and their increased requirement of this element due to the low vitamin E status, the selenium from an intravenously injected dose of sodium selenite was retained above all in the testes. After the removal of the pituitary gland, because of the decrease in the testicular mass and in the selenium content in the remaining testicular tissue, the amount of selenium in the testes was greatly reduced. After administration of pregnant mare's serum gonadotropin (PMS), due to the regeneration of the tissue and the simultaneous restoration of the selenium content, a relatively large amount of this element was shifted to the testes even though the selenium status in the other tissues was low. The results of these studies show that the selenium level in the male gonads is maintained by regulation mechanisms and that the supply of sufficient amounts of selenium to the testes has priority over the supply to other tissues.
在以产朊假丝酵母为基础的低硒和低维生素E饮食喂养10周的雄性大鼠中，与接受添加了0.25毫克硒/千克亚硒酸钠的相同基础饮食的动物相比，血液和几个组织中的硒水平以及谷胱甘肽过氧化物酶活性降低了50%至98%。然而，睾丸中的硒含量与对照动物并无差异。尽管性腺外组织中的硒水平较低，且由于维生素E水平低而对该元素的需求增加，但静脉注射的亚硒酸钠剂量中的硒主要保留在睾丸中。摘除垂体后，由于睾丸质量和剩余睾丸组织中硒含量的降低，睾丸中的硒含量大幅减少。注射孕马血清促性腺激素（PMS）后，由于组织再生和硒含量的同时恢复，即使其他组织中的硒状态较低，相对大量的这种元素也转移到了睾丸中。这些研究结果表明，雄性性腺中的硒水平通过调节机制得以维持，并且向睾丸供应足够量的硒优先于向其他组织的供应。
