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一些镰状细胞贫血患者和对照组头发中的微量元素分布。

Trace element distribution in the hair of some sickle cell anemia patients and controls.

作者信息

Oluwole A F, Asubiojo O I, Adekile A D, Filby R H, Bragg A, Grimm C I

机构信息

Department of Physics, Obafemi Awolowo University, Ile-Ife, Nigeria.

出版信息

Biol Trace Elem Res. 1990 Jul-Dec;26-27:479-84. doi: 10.1007/BF02992703.

DOI:10.1007/BF02992703
PMID:1704753
Abstract

Hair samples of some young sickle cell anemia (SCA) and control patients in Nigeria were analyzed for 12 elements, viz, Se, Hg, Cr, Fe, Zn, Co, Cu, Br, As, Sb, Na, and Sc, using Instrumental Neutron Activation Analysis (INAA). With the exception of Cu, which was found to be significantly higher in the hair of SCA patients (at the 0.05 level of the t-test), there were generally no significant differences in elemental concentrations within the two groups. A preliminary study of the elemental contents of the fingernails of the same subjects showed a higher abundance of most of the elements in nail than in hair. These preliminary results were compared with similar studies from some other parts of the world.

摘要

采用仪器中子活化分析法(INAA)对尼日利亚一些患有镰状细胞贫血(SCA)的年轻患者和对照患者的头发样本进行了12种元素的分析,即硒(Se)、汞(Hg)、铬(Cr)、铁(Fe)、锌(Zn)、钴(Co)、铜(Cu)、溴(Br)、砷(As)、锑(Sb)、钠(Na)和钪(Sc)。除了铜在SCA患者头发中的含量显著更高(t检验的P值为0.05)外,两组元素浓度总体上没有显著差异。对同一受试者指甲中元素含量的初步研究表明,指甲中大多数元素的含量高于头发。这些初步结果与世界其他一些地区的类似研究进行了比较。

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本文引用的文献

1
Analysis of zinc levels in hair for the diagnosis of zinc deficiency in man.分析头发中的锌含量以诊断人体锌缺乏症。
J Lab Clin Med. 1966 Aug;68(2):244-9.
2
Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration.阿尔茨海默病及实验性神经原纤维变性中的脑铝分布
Science. 1973 May 4;180(4085):511-3. doi: 10.1126/science.180.4085.511.
3
Zinc deficiency in sickle cell disease.
Clin Chem. 1975 Apr;21(4):582-7.