基于具有聚集诱导发光特性的四苯乙烯衍生物的荧光“点亮”生物探针。
Fluorescent "light-up" bioprobes based on tetraphenylethylene derivatives with aggregation-induced emission characteristics.
作者信息
Tong Hui, Hong Yuning, Dong Yongqiang, Häussler Matthias, Lam Jacky W Y, Li Zhen, Guo Zufeng, Guo Zhihong, Tang Ben Zhong
机构信息
Department of Chemistry, Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China.
出版信息
Chem Commun (Camb). 2006 Sep 21(35):3705-7. doi: 10.1039/b608425g. Epub 2006 Aug 2.
DOI:10.1039/b608425g
PMID:17047818
Abstract
Aggregation in poor solvents and complexation with calf thymus DNA and bovine serum albumin turn "on" the fluorescence of tetraphenylethylene derivatives, due to the restriction of intra-molecular rotations of the dyes in the aggregates and complexes.
摘要
在不良溶剂中的聚集以及与小牛胸腺DNA和牛血清白蛋白的络合会开启四苯基乙烯衍生物的荧光，这是由于染料在聚集体和络合物中的分子内旋转受到限制。
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