Lee Marshala, Entzminger Laketa, Lohsoonthorn Vitool, Williams Michelle A
Department of Preventive and Social Medicine, Faculty of Medicine, King Chulalongkorn University, Bangkok, Thailand.
J Med Assoc Thai. 2006 Aug;89(8):1213-21.
The purpose of the present cross-sectional study was to determine the relevance of several risk factors for hypertension in a Thai population.
The authors used multiple linear regression to identify factors that influenced systolic blood pressure(SBP), diastolic blood pressure (DBP), and mean arterial blood pressure (MAP) in a study of 1,398 patients.
Hypertensive risk factors were similar among men and women. Increased age, body mass index (BMI), and low educational attainment, were statistically significant risk factors for hypertension in men. For example, overweight men (BMI = 25.0-29.9 kg/m2) were 1.88 times more likely to be hypertensive (OR = 1.88, 95%CI = 1.02-3.47) as compared with men who had a normal BMI (20.0-24.9 kg/m2). Obese men (> or = 30.0 kg/m2) had an increased risk, but this association was not significant (OR = 1.40, 95%CI = 0.34-5.69). Similar risk factors were identified among women. Overweight women had a 1.74-increased risk for hypertension (OR = 1.74, 95%CI = 1.13-2.69). The corresponding risk was increased 3-fold among obese women (OR = 3.05, 95%CI = 1.76-5.29). Among men, age and BMI were positively associated with increased SBP, DBP and MAP Men > or = 60 years of age had an increase in SBP (beta = 18.89, p < 0.001), DBP (beta = 5.53, p < 0.001), and MAP (beta = 9.89, p < 0.001) values as compared with the referent group (< 40 years). Similar associations were noted among women.
Hypertension risk factors observed in this Thai population are similar to those found in Western populations. Prospective studies are needed to evaluate rigorously causal relationships between risk factors and hypertension.
本横断面研究的目的是确定泰国人群中几种高血压危险因素的相关性。
作者在一项对1398名患者的研究中使用多元线性回归来确定影响收缩压(SBP)、舒张压(DBP)和平均动脉压(MAP)的因素。
高血压危险因素在男性和女性中相似。年龄增加、体重指数(BMI)升高和低教育程度是男性高血压的统计学显著危险因素。例如,超重男性(BMI = 25.0 - 29.9 kg/m²)患高血压的可能性是BMI正常(20.0 - 24.9 kg/m²)男性的1.88倍(OR = 1.88,95%CI = 1.02 - 3.47)。肥胖男性(≥30.0 kg/m²)风险增加,但这种关联不显著(OR = 1.40,95%CI = 0.34 - 5.69)。在女性中也发现了类似的危险因素。超重女性患高血压的风险增加1.74倍(OR = 1.74,95%CI = 1.13 - 2.69)。肥胖女性的相应风险增加了3倍(OR = 3.05,95%CI = 1.76 - 5.29)。在男性中,年龄和BMI与SBP、DBP和MAP升高呈正相关。与参照组(<40岁)相比,年龄≥60岁的男性SBP(β = 18.89,p < 0.001)、DBP(β = 5.53,p < 0.001)和MAP(β = 9.89,p < 0.001)值升高。在女性中也观察到类似的关联。
在这个泰国人群中观察到的高血压危险因素与西方人群中发现的相似。需要进行前瞻性研究来严格评估危险因素与高血压之间的因果关系。