Adamo Mauro F A, Duffy Eleanor F
Centre for Synthesis and Chemical Biology (CSCB), Department of Pharmaceutical and Medicinal Chemistry, The Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Dublin, Ireland.
Org Lett. 2006 Oct 26;8(22):5157-9. doi: 10.1021/ol062151y.
A four component one-pot procedure (4-MC) was developed to assemble 3-heteroarylpropionic acids from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography. [reaction: see text]
开发了一种四组分一锅法（4-MC），用于从市售原料组装3-杂芳基丙酸。这种新方法能高产率地得到目标化合物，且无需使用色谱法。[反应：见正文]
