Tanaka K, Nakamura E, Naitoh K, Utsunomiya I, Matsuo K, Osabe S, Honda J, Yoshida K, Egami K, Natori H
First Department of Internal Medicine, Kurume University School of Medicine.
Rinsho Ketsueki. 1990 Nov;31(11):1851-5.
Relapsing polychondritis is a rare disorder of uncertain origin characterized by recurrent inflammation of cartilage. A case of myelodysplastic syndrome (MDS) associated with relapsing polychondritis is reported. A 60-year-old man who had been diagnosed as MDS was admitted because of pain and swelling in the bilateral preauricular regions and cheek. A diagnosis of relapsing polychondritis was made by coexistence of auricular chondritis, arthropathy, ocular inflammation and audio-vestibular disturbance. He also developed ocular palsies and optic neuritis. He was treated with prednisolone, azathioprine, dapsone, and then with steroid pulse therapy. Moreover, plasmapheresis and high dose gamma-globulin therapy were undertaken. However, all these treatments were unsuccessful and he died of respiratory failure.
复发性多软骨炎是一种病因不明的罕见疾病，其特征为软骨反复发炎。本文报告一例与复发性多软骨炎相关的骨髓增生异常综合征（MDS）。一名60岁男性，此前已被诊断为MDS，因双侧耳前区域和脸颊疼痛肿胀入院。根据耳软骨炎、关节病、眼部炎症和听觉前庭功能障碍的共存情况，诊断为复发性多软骨炎。他还出现了眼肌麻痹和视神经炎。给予泼尼松龙、硫唑嘌呤、氨苯砜治疗，随后进行类固醇冲击治疗。此外，还进行了血浆置换和大剂量丙种球蛋白治疗。然而，所有这些治疗均未成功，患者死于呼吸衰竭。
