Sasmaz Tayyar, Kurt Ahmet Oner, Ozturk Candan, Bugdayci Resul, Oner Seva
Deparment of Public Health, Mersin University Faculty of Medicine, Mersin, Turkey.
Vaccine. 2007 Jan 15;25(5):912-7. doi: 10.1016/j.vaccine.2006.09.033. Epub 2006 Oct 6.
The aim of this study was to determine the rubella seroprevalence in women of reproductive age. This cross-sectional study was conducted on women aged 15-49 years. Serologic studies were performed by using the ELISA method. The number of women enrolled in the study was 607, the mean age was 30.7+/-9.3 years and 13.2% of the participants were living in the rural area. Rubella seroprevalence was 55.0%. This ratio was 77.5% in women living in the rural area (p<0.001). There were no statistically significant correlations between immunity to rubella and other socio-demographic characteristics. In conclusion, women in this age group are advised to have a single dose of rubella vaccination in order to avoid CRS before pregnancy.
本研究的目的是确定育龄妇女的风疹血清流行率。这项横断面研究针对的是15至49岁的女性。采用酶联免疫吸附测定（ELISA）法进行血清学研究。纳入该研究的女性有607名，平均年龄为30.7±9.3岁，13.2%的参与者生活在农村地区。风疹血清流行率为55.0%。生活在农村地区的女性这一比例为77.5%（p<0.001）。风疹免疫力与其他社会人口学特征之间无统计学显著相关性。总之，建议该年龄组的女性在怀孕前接种一剂风疹疫苗，以避免先天性风疹综合征（CRS）。
