Choi Sang-Ho, Woo Jun Hee, Jeong Jin-Yong, Kim Nam Joong, Kim Mi-Na, Kim Yang Soo, Ryu Jiso
Division of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, and Center for Antimicrobial Resistance and Microbial Genetics, University of Ulsan, Seoul 138-736, South Korea.
Diagn Microbiol Infect Dis. 2006 Nov;56(3):337-9. doi: 10.1016/j.diagmicrobio.2006.08.012. Epub 2006 Oct 17.
Staphylococcus saprophyticus is a well-known cause of acute uncomplicated urinary tract infection in young women. However, the clinical significance of this organism isolated from blood culture has not been determined. We assessed the clinical significance and characteristics of S. saprophyticus identified on blood culture. A total of 24 patients were identified, and 7 patients (29.2%) were considered to have clinically significant bacteremia. Of the 7 patients with clinically significant bacteremia, hematologic malignancy was the most common underlying illness (5 patients), and tunneled-central venous catheter was the most common portal of entry (4 patients). In no case did S. saprophyticus bacteremia originate from the urinary tract. One patient died during hospitalization. However, the death was not directly related to bacteremia. In conclusion, our data suggest that bacteremia caused by S. saprophyticus is most commonly associated with tunneled-central venous catheter in patients with hematologic malignancies and may be associated with a lower risk of mortality.
腐生葡萄球菌是年轻女性急性单纯性尿路感染的常见病因。然而，从血培养中分离出的这种微生物的临床意义尚未确定。我们评估了血培养中鉴定出的腐生葡萄球菌的临床意义和特征。共识别出24例患者，其中7例（29.2%）被认为患有具有临床意义的菌血症。在7例具有临床意义的菌血症患者中，血液系统恶性肿瘤是最常见的基础疾病（5例），隧道式中心静脉导管是最常见的感染入口（4例）。腐生葡萄球菌菌血症无一例起源于泌尿系统。1例患者在住院期间死亡。然而，死亡与菌血症无直接关系。总之，我们的数据表明，腐生葡萄球菌引起的菌血症在血液系统恶性肿瘤患者中最常与隧道式中心静脉导管相关，且可能与较低的死亡风险相关。
