Calero F, Villegas A, Porres A, Valverde F, del Potro E, Sánchez P, Luque J M, Espinós D
Servicio de Hematologia, Hospital Universitario San Carlos, Universidad Complutense de Madrid, Spain.
Nouv Rev Fr Hematol (1978). 1990;32(4):265-70.
We present the hematologic data of 825 cases of beta-thalassemia trait (687 cases of beta-thalassemia trait and 138 cases of delta beta-thalassemia trait). There were no significant differences between the red cell indices of the patients with beta and delta beta-thalassemia trait. In patients with beta-thalassemia trait, MCV was significantly reduced in 97% of the males and 99% of the females. All the patients with delta beta-thalassemia trait showed low MCV values. Red cell morphology was altered in the vast majority of cases, with basophilic stippling in 96% of the patients. Most patients came from provinces with the highest incidence of malaria in the past.
我们呈现了825例β-地中海贫血特征患者(687例β-地中海贫血特征患者和138例δβ-地中海贫血特征患者)的血液学数据。β-地中海贫血特征患者与δβ-地中海贫血特征患者的红细胞指数之间无显著差异。在β-地中海贫血特征患者中,97%的男性和99%的女性MCV显著降低。所有δβ-地中海贫血特征患者的MCV值均较低。绝大多数病例的红细胞形态发生改变,96%的患者出现嗜碱性点彩。大多数患者来自过去疟疾发病率最高的省份。