Prehn A W, Vawter D E, Gervais K G, DeVries R G, Garrett J E, Freeman T B, McIndoo T Q
Minnesota Center for Health Care Ethics, 601 25th Avenue South, Minneapolis, MN 55454, USA.
Neurology. 2006 Oct 24;67(8):1503-5. doi: 10.1212/01.wnl.0000240221.78518.5e.
North American researchers' perspectives on designing neurosurgical implant studies for Parkinson disease (PD) challenged the custom of holding surgical trials to less stringent evidentiary standards than other clinical studies. Researchers supported placebo surgery-controlled trials. The framework they used to design and evaluate studies both of deep brain stimulation and cellular implants for PD may be applicable to a broad range of surgical implants for other disorders.
北美研究人员对于帕金森病（PD）神经外科植入物研究设计的观点，对将外科手术试验的证据标准设定得比其他临床研究更为宽松的惯例提出了挑战。研究人员支持采用假手术对照试验。他们用于设计和评估针对PD的深部脑刺激和细胞植入物研究的框架，可能适用于针对其他疾病的广泛外科植入物。
