Swift Teresa L
University of Bristol, UK.
J Empir Res Hum Res Ethics. 2012 Jul;7(3):15-28. doi: 10.1525/jer.2012.7.3.15.
This study reports on qualitative research conducted in the UK with people with Parkinson's Disease and their relatives on the subject of "sham surgery." It explores attitudes toward sham surgery and reasoning about hypothetical participation in a sham-controlled trial. Results showed that attitudes toward sham surgery may not necessarily predict trial participation behavior. A small majority of interviewees deemed sham surgery ethically acceptable with certain provisos, but hypothetical participation was driven primarily by disease severity and a lack of standard treatment options, with a preference for receiving the real surgery over sham. Ethical implications for patient equipoise and the autonomy of patients' research participation decisions are discussed.
本研究报告了在英国针对帕金森病患者及其亲属开展的关于“假手术”主题的定性研究。它探讨了对假手术的态度以及关于假设参与假手术对照试验的推理。结果表明，对假手术的态度不一定能预测试验参与行为。一小部分受访者认为在某些条件下假手术在伦理上是可以接受的，但假设参与主要受疾病严重程度和缺乏标准治疗方案的驱动，相较于假手术，更倾向于接受真正的手术。文中还讨论了对患者 equipoise 以及患者研究参与决策自主性的伦理影响。
