Clayman Mark A, Clayman Scott M, Seagle M Brent
Division of Plastic and Reconstructive Surgery at the University of Florida College of Medicine, Gainesville, FL, USA.
Ann Plast Surg. 2006 Nov;57(5):581-4. doi: 10.1097/01.sap.0000237085.59782.65.
Frey syndrome represents a fascinating example of how nerve regeneration can go awry. The syndrome is characterized by profuse facial sweating and flushing that occurs when salivation is stimulated. It can develop following a variety of insults but is most commonly encountered as a complication of parotidectomy. Consequently, it is mainly head and neck surgeons who see and treat this disorder; however, it is important for other clinicians to recognize what these unusual symptoms represent. Diagnosis may be based either on clinical presentation or through objective testing methods. Potential negative social and psychologic implications of this condition can be significant, and treatment ranging from topical agents to local injections of botulinum toxin (Botox) to surgical intervention should be offered to patients. In this article, we present an up-to-date review of the surgical and medical treatment of this syndrome.
弗雷综合征是神经再生出现差错的一个引人关注的例子。该综合征的特征是在唾液分泌受到刺激时，面部会大量出汗并泛红。它可在遭受多种损伤后发生，但最常见于腮腺切除术后的并发症。因此，主要是头颈外科医生会诊治这种疾病；然而，其他临床医生认识到这些异常症状代表着什么也很重要。诊断可基于临床表现或通过客观检测方法。这种情况潜在的负面社会和心理影响可能很大，应向患者提供从局部用药到局部注射肉毒杆菌毒素（保妥适）再到手术干预等一系列治疗方法。在本文中，我们对该综合征的手术和药物治疗进行了最新综述。
