小鼠肝脏3':5'-环磷酸腺苷（环磷腺苷）水平与组织相容性-2基因型的关联
Association of mouse liver adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels with histocompatibility-2 genotype.
作者信息
Meruelo D, Edidin M
出版信息
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2644-8. doi: 10.1073/pnas.72.7.2644.
Abstract
When the content of cyclic AMP (cAMP) was compared in livers of a series of congenic mouse strains differing at the H-2 locus, significant variation in concentration of cAMP per unit wet weight was found among strains, and also for animals of a given strain with increasing age. For a given age, from 8 to 22 weeks, cAMP levels in liver of H-2a and H-2b genotype animals were significantly higher than that in liver of H-2k type animals. This difference was seen whether the H-2 gene was on the genetic background of strain C57BL/10, C3H, or A. Levels of cAMP in livers of H-2d animals were between those of H-2a and H-2k animals.
摘要
当对一系列在H-2位点存在差异的同源近交系小鼠肝脏中的环磷酸腺苷（cAMP）含量进行比较时，发现不同品系之间每单位湿重的cAMP浓度存在显著差异，而且对于给定品系的动物，随着年龄增长也存在差异。对于8至22周龄的给定年龄组，H-2a和H-2b基因型动物肝脏中的cAMP水平显著高于H-2k型动物肝脏中的水平。无论H-2基因位于C57BL/10、C3H或A品系的遗传背景上，这种差异都能观察到。H-2d动物肝脏中的cAMP水平介于H-2a和H-2k动物之间。
相似文献
1
Association of mouse liver adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels with histocompatibility-2 genotype.小鼠肝脏3':5'-环磷酸腺苷（环磷腺苷）水平与组织相容性-2基因型的关联
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2644-8. doi: 10.1073/pnas.72.7.2644.
2
Translocation of cytoplasmic protein kinase and cyclic adenosine monophosphate-binding protein to intracellular acceptor sites.细胞质蛋白激酶和环磷酸腺苷结合蛋白向细胞内受体位点的转位。
Adv Cyclic Nucleotide Res. 1975;5:281-306.
3
Retinal cAMP levels in the mouse: lack of effect of the major histocompatibility locus.
J Hered. 1983 Jul-Aug;74(4):310. doi: 10.1093/oxfordjournals.jhered.a109797.
4
Genetic correlations between initial sensitivity to Ethanol and brain cAMP signaling in inbred and selectively bred mice.近交系和选择性培育小鼠中乙醇初始敏感性与脑cAMP信号传导之间的遗传相关性。
Alcohol Clin Exp Res. 2001 Jun;25(6):791-9.
5
Glycogenolytic rates and cAMP in livers of rats running at different treadmill speeds.
Am J Physiol. 1983 Sep;245(3):R353-6. doi: 10.1152/ajpregu.1983.245.3.R353.
6
The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.组织相容性-2连锁的Ss-Slp区域在小鼠补体控制中的作用。
Proc Natl Acad Sci U S A. 1973 Mar;70(3):863-4. doi: 10.1073/pnas.70.3.863.
7
Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues.牛和大鼠组织中的3':5'-环磷酸腺苷结合蛋白
Biochem J. 1976 Nov;159(2):423-37. doi: 10.1042/bj1590423.
8
Hepatic clearance of adenosine 3:5-cyclic monophosphate from plasma in the rat.大鼠血浆中3:5 - 环磷酸腺苷的肝脏清除率
Biochem J. 1975 Feb;146(2):509-12. doi: 10.1042/bj1460509.
9
Cyclic AMP-dependent protein kinase I: cyclic nucleotide binding, structural changes, and release of the catalytic subunits.环磷酸腺苷依赖性蛋白激酶I：环核苷酸结合、结构变化及催化亚基的释放
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1591-5. doi: 10.1073/pnas.78.3.1591.
10
[Effect of prolonged hypo- or hyperkinesia on the cAMP content in the liver, brain and muscles of rats].
Vet Med Nauki. 1984;21(5):66-70.
引用本文的文献
1
Genes in mice that affect susceptibility to cortisone-induced cleft palate are closely linked to Ir genes on chromosomes 2 and 17.小鼠中影响对可的松诱导腭裂易感性的基因与2号和17号染色体上的Ir基因紧密连锁。
Proc Natl Acad Sci U S A. 1981 May;78(5):3147-50. doi: 10.1073/pnas.78.5.3147.
2
H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17.H-2单倍型、基因与抗原：第二次列表。一、17号染色体上的非H-2基因座
Immunogenetics. 1982;16(4):285-317. doi: 10.1007/BF00372302.
3
Interaction between major histocompatibility complex antigens and epidermal growth factor receptors on human cells.人类细胞上主要组织相容性复合体抗原与表皮生长因子受体之间的相互作用。
J Cell Biol. 1984 Feb;98(2):725-31. doi: 10.1083/jcb.98.2.725.
4
An unusual symmetric recombinant between adenovirus type 12 DNA and human cell DNA.12型腺病毒DNA与人类细胞DNA之间一种异常的对称重组体。
Proc Natl Acad Sci U S A. 1981 May;78(5):3142-6. doi: 10.1073/pnas.78.5.3142.
5
Insulin binding to human B lymphoblasts is a function of HLA haplotype.胰岛素与人类B淋巴母细胞的结合是HLA单倍型的一种功能。
Proc Natl Acad Sci U S A. 1987 Mar;84(5):1351-5. doi: 10.1073/pnas.84.5.1351.
6
HLA-B18 is associated with decreased levels of isoproterenol-stimulated cAMP in lymphocytes.HLA - B18与淋巴细胞中异丙肾上腺素刺激的环磷酸腺苷（cAMP）水平降低有关。
Am J Hum Genet. 1985 Jan;37(1):124-32.
7
DNA polymorphisms defined by the Tu108 probe map to the Tla region of mouse chromosome 17.
Biochem Genet. 1988 Aug;26(7-8):475-80. doi: 10.1007/BF02399414.
8
Localization of the papain cleavage site of H-2 glycoproteins.H-2糖蛋白的木瓜蛋白酶切割位点的定位
Proc Natl Acad Sci U S A. 1976 Mar;73(3):915-8. doi: 10.1073/pnas.73.3.915.
9
Effect of the H-2 gene complex rates of fibroblast intercellular adhesion.H-2基因复合体对成纤维细胞细胞间黏附率的影响。
J Cell Biol. 1978 May;77(2):377-88. doi: 10.1083/jcb.77.2.377.
10
Estrogen receptor in uteri of mice of different H-2 genotypes.
Experientia. 1979 Aug 15;35(8):1103-4. doi: 10.1007/BF01949969.
本文引用的文献
1
HISTOCOMPATIBILITY GENES OF MICE. V. FIVE NEW HISTOCOMPATIBILITY LOCI IDENTIFIED BY CONGENIC RESISTANT LINES ON A C57B 10 BACKGROUND.小鼠的组织相容性基因。V. 在C57B10背景上通过同源抗性品系鉴定出的五个新的组织相容性位点。
Transplantation. 1965 Mar;3:235-52. doi: 10.1097/00007890-196503000-00011.
2
THE CELLULAR LOCATION OF ADENYL CYCLASE IN THE PIGEON ERYTHROCYTE.鸽红细胞中腺苷酸环化酶的细胞定位
J Biol Chem. 1963 Sep;238:3016-23.
3
Factors affecting the activity of muscle glycogen synthetase. 3. The reaction with adenosine triphosphate Mg++, and cyclic 3'5'-adenosine monophosphate.影响肌肉糖原合成酶活性的因素。3. 与三磷酸腺苷镁离子及环磷酸腺苷的反应
Arch Biochem Biophys. 1966 Sep 26;116(1):39-43. doi: 10.1016/0003-9861(66)90009-9.
4
The effect of histocompatibility-2 type on response to friend leukemia virus in mice.组织相容性-2类型对小鼠对Friend白血病病毒反应的影响。
J Exp Med. 1968 Mar 1;127(3):465-73. doi: 10.1084/jem.127.3.465.
5
A rapid, quantitative fluorescence assay for cell damage by cytotoxic antibodies.一种用于检测细胞毒性抗体所致细胞损伤的快速定量荧光测定法。
J Immunol. 1970 May;104(5):1303-6.
6
Cytological identification of the chromosome carrying the IXth linkage group (including H-2) in the house mouse.小家鼠中携带第IX连锁群（包括H-2）的染色体的细胞学鉴定。
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1594-7. doi: 10.1073/pnas.68.7.1594.
7
Genetic control of haemolytic complement in mice: association with H-2.小鼠溶血性补体的遗传控制：与H-2的关联。
Folia Biol (Praha). 1972;18(4):237-43.
8
9
Genetic control of the immune response. Mapping of the Ir-1 locus.免疫反应的遗传控制。Ir-1基因座的定位。
J Exp Med. 1972 Jun 1;135(6):1259-78. doi: 10.1084/jem.135.6.1259.
10
New lymphocyte antigens controlled by the Ir-IgG region of the H-2 gene complex.由H-2基因复合体的Ir-IgG区域控制的新淋巴细胞抗原。
Transplantation. 1974 Jan 1;17(1):122-5.
Zotero 插件