[罗布麻叶中黄酮类化合物的研究]

[Study on flavonoids in leaves of Apocynum ventum].

作者信息

Li Li-Hong, Yuan Zhong

机构信息

Department of Analysis of Traditional Chinese Medicine, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2006 Aug;31(16):1337-40.

PMID:17061555

Abstract

OBJECTIVE

To study the flavonoids in the leaves of Apocynum ventum.

METHOD

Compounds were separated by repeated polyacrylamide column chromatgraphy combined with Sephadex LH-20 column chromatgraphy, their structures were confirmed by the analysis of spectral data and physicochemical properties.

RESULT

Six compounds were isolated from A. ventum. They were elucidated as quercetin (1), kaempferol (2), kaempferol-3-O-(6"-O-acetyl)-beta-D-glucopyranoside (3), quercetin-3-O-(6"-O-acetyl )-beta-D-glucopyranoside (4), quercetin-3-O-(6"-O-acetyl)-beta-D-galactopyranoside (5), kaempferol-7-O-alpha-L-rhamnopyranoside (6).

CONCLUSION

Compound 5 and 6 were isolated from the genus Apocynum for the first time.

摘要

目的

研究罗布麻叶中的黄酮类化合物。

方法

采用反复聚丙烯酰胺柱色谱结合葡聚糖凝胶LH - 20柱色谱分离化合物，通过光谱数据分析和理化性质确定其结构。

结果

从罗布麻中分离得到6个化合物，分别鉴定为槲皮素（1）、山柰酚（2）、山柰酚 - 3 - O -（6″ - O - 乙酰基）- β - D - 吡喃葡萄糖苷（3）、槲皮素 - 3 - O -（6″ - O - 乙酰基）- β - D - 吡喃葡萄糖苷（4）、槲皮素 - 3 - O -（6″ - O - 乙酰基）- β - D - 吡喃半乳糖苷（5）、山柰酚 - 7 - O - α - L - 鼠李糖苷（6）。