Pahlavan Payam S, Niroomand Feraydoon
Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany.
Clin Cardiol. 2006 Oct;29(10):439-43. doi: 10.1002/clc.4960291005.
Coronary artery ectasia (CAE) is found in 0.3-5% of patients undergoing coronary angiography. Atherosclerosis is the main cause, followed by Kawasaki disease and infectious emboli. The exact pathogenesis has not been diagnosed as yet, but an inflammatory process is underlying. Symptoms, if present, are usually related to myocardial ischemia. Angiography is the mainstay for diagnosis. The prognosis is generally favorable. Thromboembolic complications are rare with antiplatelet therapy, and spontaneous rupture generally is rare but occurs more commonly in Kawasaki disease. Management varies from antithrombotic therapy to surgical ligation. Controlling coronary heart disease risk factors sharply affects the prognosis in patients with CAE.
冠状动脉扩张(CAE)在接受冠状动脉造影的患者中占0.3%-5%。动脉粥样硬化是主要病因,其次是川崎病和感染性栓子。确切的发病机制尚未明确,但炎症过程是其基础。若出现症状,通常与心肌缺血有关。血管造影是诊断的主要手段。总体预后良好。抗血小板治疗时血栓栓塞并发症罕见,自发性破裂一般也少见,但在川崎病中更常见。治疗方法从抗血栓治疗到手术结扎不等。严格控制冠心病危险因素对CAE患者的预后有很大影响。