Rodden Ann M, Spicer Leigh, Diaz Vanessa A, Steyer Terrence E
Medical University of South Carolina, Department of Family Medicine, 295 Calhoun Street, Charleston, SC 29425, USA.
Intensive Crit Care Nurs. 2007 Feb;23(1):51-5. doi: 10.1016/j.iccn.2006.08.006. Epub 2006 Oct 24.
Results from previous studies evaluating the effect of nail polish on oxygen saturation (SpO(2)) determined by pulse oximeter monitors are inconsistent. Establishing the effect of nail polish on SpO(2) is relevant to clinical practice, since removing nail polish requires clinical time and supplies.
The objective of this study was to determine if fingernail polish affects SpO(2) as measured by two different pulse oximeter machines.
Absorption spectra of 10 nail polish colors were obtained by spectrophotometry. Twenty-seven healthy volunteers with SpO(2)> or =95% participated. Using the Nellcor N20 and N595 pulse oximeters, the mean SpO(2) was measured on each of 10 nails with and without nail polish and using a side-to-side configuration. Means were compared using paired t-tests.
Mean SpO(2) had a statistically significant decrease with brown and blue nail polish using both machines (p<0.05) but this was not clinically significant (<1% difference). Using the side-to-side configuration, the N595 oximeter had a statistically significant decrease in mean SpO(2) with red nail polish but again this was not clinically significant.
Fingernail polish does not cause a clinically significant change in pulse oximeter readings in healthy people.
以往评估指甲油对脉搏血氧仪监测的血氧饱和度（SpO₂）影响的研究结果并不一致。确定指甲油对SpO₂的影响与临床实践相关，因为去除指甲油需要临床时间和耗材。
本研究的目的是确定指甲油是否会影响两种不同脉搏血氧仪测得的SpO₂。
通过分光光度法获得10种指甲油颜色的吸收光谱。27名血氧饱和度（SpO₂）≥95%的健康志愿者参与了研究。使用Nellcor N20和N595脉搏血氧仪，在每根指甲涂抹指甲油和未涂抹指甲油的情况下，采用左右对照的方式测量平均SpO₂。采用配对t检验比较平均值。
使用这两种仪器时，棕色和蓝色指甲油均使平均SpO₂出现统计学上的显著下降（p<0.05），但在临床上并不显著（差异<1%）。采用左右对照的方式时，N595血氧仪测得红色指甲油使平均SpO₂出现统计学上的显著下降，但同样在临床上并不显著。
指甲油不会使健康人的脉搏血氧仪读数出现具有临床意义的变化。
