Hinkelbein Jochen, Koehler Heike, Genzwuerker Harald V, Fiedler Fritz
University Clinic for Anaesthesiology and Intensive Care Medicine, Medical Faculty Mannheim, Ruprecht-Karls-University Heidelberg, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Resuscitation. 2007 Jul;74(1):75-82. doi: 10.1016/j.resuscitation.2006.11.018. Epub 2007 Mar 13.
Pulse oximetry is the most common technique to monitor oxygen saturation (SpO(2)) during intensive care therapy. However, intermittent co-oximetry is still the "gold standard" (SaO(2)). Besides acrylic nails, numerous other factors have been reported to interfere with pulse oximetry. Data of measurements with artificial finger nails are not sufficiently published.
A prospective clinical-experimental trial in mechanically ventilated and critically ill patients of an ICU was performed. Patients were randomly assigned to either group S (S: Siemens pulse oximeter) or group P (P: Philips pulse oximeter) prior to the measurements. SpO(2) was determined in each patient three times alternately in standard ((N)SpO(2)) and sideways position at the natural nail ((N90)SpO(2)). For the reference measurements oxygen saturation was measured by means of a haemoximeter (co-oximetry). Thereafter, SpO(2) was obtained at the acrylic finger nail in the same way ((A)SpO(2) and (A90)SpO(2)). Bias was calculated as DeltaS=(N)SpO(2)-SaO(2) and DeltaS=(A)SpO(2)-SaO(2). Accuracy (mean difference) and precision (standard deviation) were used to determine the measurement discrepancy. P<0.05 was considered significant.
Accuracy and precision without acrylic nails applied were comparable to SaO(2) in both groups (n.s.). With acrylic nails applied a bias of DeltaS=-1.1+/-3.14% for group S (P=0.00522) and a bias of DeltaS=+0.8+/-3.04% for group P was calculated (n.s.).
Acrylic finger nails may impair the measurement of oxygen saturation depending on the pulse oximeter used and may cause significant inaccuracy. Hence, removal of artificial acrylic finger nails may be helpful to assure an accurate and precise measurement with pulse oximetry.
脉搏血氧饱和度测定法是重症监护治疗期间监测血氧饱和度(SpO₂)最常用的技术。然而,间歇性血氧定量法仍是“金标准”(SaO₂)。除了丙烯酸指甲外,已有大量其他因素被报道会干扰脉搏血氧饱和度测定法。关于使用人造指甲进行测量的数据发表得并不充分。
在一家重症监护病房对机械通气的重症患者进行了一项前瞻性临床实验研究。在测量前,将患者随机分为S组(S:西门子脉搏血氧仪)或P组(P:飞利浦脉搏血氧仪)。在每位患者的自然指甲上,分别在标准位置((N)SpO₂)和侧向位置((N90)SpO₂)交替测定三次SpO₂。作为参考测量,通过血氧计(血氧定量法)测量血氧饱和度。此后,以相同方式在丙烯酸指甲上获取SpO₂((A)SpO₂和(A90)SpO₂)。偏差计算为ΔS = (N)SpO₂ - SaO₂以及ΔS = (A)SpO₂ - SaO₂。使用准确度(平均差值)和精密度(标准差)来确定测量差异。P < 0.05被认为具有统计学意义。
两组在未使用丙烯酸指甲时的准确度和精密度与SaO₂相当(无统计学差异)。使用丙烯酸指甲时,S组计算出的偏差为ΔS = -1.1 ± 3.14%(P = 0.00522),P组计算出的偏差为ΔS = +0.8 ± 3.04%(无统计学差异)。
丙烯酸指甲可能会根据所使用的脉搏血氧仪影响血氧饱和度的测量,并可能导致显著的不准确。因此,去除人造丙烯酸指甲可能有助于确保脉搏血氧饱和度测定法的准确和精确测量。