来自欧洲的对泰利霉素不敏感的肺炎链球菌临床分离株。
Telithromycin-nonsusceptible clinical isolates of Streptococcus pneumoniae from Europe.
作者信息
Al-Lahham Adnan, Appelbaum Peter C, van der Linden Mark, Reinert Ralf René
机构信息
Institute for Medical Microbiology, National Reference Center for Streptococci, University Hospital (RWTH), Pauwelsstr. 30, Aachen, Germany.
出版信息
Antimicrob Agents Chemother. 2006 Nov;50(11):3897-900. doi: 10.1128/AAC.00057-06.
Abstract
Telithromycin-nonsusceptible pneumococcal clinical isolates (n = 17) were analyzed for their antimicrobial susceptibility, macrolide resistance mechanisms, and genetic relatedness. All strains showed the erm(B) genotype and showed a wide range of combinations of macrolide resistance mechanisms. The predominant clone (n = 7) was serotype 14, sequence type 143.
摘要
对17株对泰利霉素不敏感的肺炎球菌临床分离株进行了抗菌药敏性、大环内酯类耐药机制及基因相关性分析。所有菌株均表现出erm(B)基因型，且呈现出多种大环内酯类耐药机制组合。主要克隆株（7株）为14型血清型、序列型143。
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