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本文引用的文献

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Streptococcus pneumoniae isolates resistant to telithromycin.对泰利霉素耐药的肺炎链球菌分离株。
Antimicrob Agents Chemother. 2006 May;50(5):1855-8. doi: 10.1128/AAC.50.5.1855-1858.2006.
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Sampling the antibiotic resistome.对抗生素耐药基因组进行采样。
Science. 2006 Jan 20;311(5759):374-7. doi: 10.1126/science.1120800.
3
Relationship between the original multiply resistant South African isolates of Streptococcus pneumoniae from 1977 to 1978 and contemporary international resistant clones.1977年至1978年南非肺炎链球菌原始多重耐药菌株与当代国际耐药克隆之间的关系。
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Emergence of a Streptococcus pneumoniae clinical isolate highly resistant to telithromycin and fluoroquinolones.出现对泰利霉素和氟喹诺酮类高度耐药的肺炎链球菌临床分离株。
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Ketolide resistance in Streptococcus pyogenes correlates with the degree of rRNA dimethylation by Erm.化脓性链球菌对酮内酯类药物的耐药性与Erm介导的rRNA甲基化程度相关。
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Mechanisms of resistance to telithromycin in Streptococcus pneumoniae.肺炎链球菌对泰利霉素的耐药机制
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Telithromycin activity is reduced by efflux in Streptococcus pyogenes.在化脓性链球菌中，泰利霉素的活性会因外排作用而降低。
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Molecular characterisation of macrolide resistance mechanisms of Streptococcus pneumoniae and Streptococcus pyogenes isolated in Germany, 2002-2003.2002 - 2003年德国分离的肺炎链球菌和化脓性链球菌大环内酯类耐药机制的分子特征
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Activities of telithromycin against 13,874 Streptococcus pneumoniae isolates collected between 1999 and 2003.泰利霉素对1999年至2003年间收集的13874株肺炎链球菌的活性。
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来自欧洲的对泰利霉素不敏感的肺炎链球菌临床分离株。

Telithromycin-nonsusceptible clinical isolates of Streptococcus pneumoniae from Europe.

作者信息

Al-Lahham Adnan, Appelbaum Peter C, van der Linden Mark, Reinert Ralf René

机构信息

Institute for Medical Microbiology, National Reference Center for Streptococci, University Hospital (RWTH), Pauwelsstr. 30, Aachen, Germany.

出版信息

Antimicrob Agents Chemother. 2006 Nov;50(11):3897-900. doi: 10.1128/AAC.00057-06.

DOI:10.1128/AAC.00057-06
PMID:17065627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1635229/
Abstract

Telithromycin-nonsusceptible pneumococcal clinical isolates (n = 17) were analyzed for their antimicrobial susceptibility, macrolide resistance mechanisms, and genetic relatedness. All strains showed the erm(B) genotype and showed a wide range of combinations of macrolide resistance mechanisms. The predominant clone (n = 7) was serotype 14, sequence type 143.

摘要

对17株对泰利霉素不敏感的肺炎球菌临床分离株进行了抗菌药敏性、大环内酯类耐药机制及基因相关性分析。所有菌株均表现出erm(B)基因型，且呈现出多种大环内酯类耐药机制组合。主要克隆株（7株）为14型血清型、序列型143。