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在欧洲鼹鼠(Talpa europaea)中进行的动物荧光原位杂交(Zoo-FISH)检测到了所有与人类同源的北方真兽类祖先染色体关联。

Zoo-FISH in the European mole (Talpa europaea) detects all ancestral Boreo-Eutherian human homologous chromosome associations.

作者信息

Volleth M, Müller S

机构信息

Department of Human Genetics, Otto-von-Guericke-University, Magdeburg.

出版信息

Cytogenet Genome Res. 2006;115(2):154-7. doi: 10.1159/000095236.

Abstract

Zoo-FISH with human whole-chromosome paint probes delineated syntenic association of human homologous chromosome segments 3-21, 14-15, 16-19, 4-8, 7-16 and 12-22 (twice) in the European mole (Talpa europaea, Talpidae, Eulipotyphla, Mammalia). These segment associations represent shared ancestral Boreo-Eutherian traits, half of which were previously not described for Eulipotyphla. The karyotype of the European mole acquired a minimum of 19 translocations and six inversions compared to the presumed Boreo-Eutherian ancestor.

摘要

使用人类全染色体涂染探针进行的荧光原位杂交(Zoo-FISH)在欧洲鼹鼠(Talpa europaea,鼹科,真盲缺目,哺乳动物)中描绘出了人类同源染色体片段3-21、14-15、16-19、4-8、7-16和12-22(两次)的同线关联。这些片段关联代表了共同的祖传北真兽类特征,其中一半此前未在真盲缺目中描述过。与推测的北真兽类祖先相比,欧洲鼹鼠的核型至少发生了19次易位和6次倒位。

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