Schmued L, Kyriakidis K, Heimer L
Department of Otolaryngology, University of Virginia, Charlottesville 22908.
Brain Res. 1990 Aug 27;526(1):127-34. doi: 10.1016/0006-8993(90)90258-d.
A number of fluorescent dextrans were screened for axonal transport properties within the rat CNS. One compound, Fluoro-Ruby (FR), was found to be particularly sensitive for demonstrating retrograde and particularly anterograde axonal transport. The tracer may be either pressure or iontophoretically injected, and the fixed tissue can be examined without histochemical processing. The technique can be combined with a wide variety of other neuroanatomical methods.
对多种荧光葡聚糖进行了筛选，以研究其在大鼠中枢神经系统内的轴突运输特性。发现一种名为氟鲁比（FR）的化合物在显示逆行性尤其是顺行性轴突运输方面特别敏感。该示踪剂可以通过压力注射或离子电渗法注射，固定后的组织无需进行组织化学处理即可检查。该技术可以与多种其他神经解剖学方法相结合。
