来自多种哺乳动物来源的潜在胶原酶的胰蛋白酶激活作用。

Trypsin activation of latent collagenase from several mammalian sources.

作者信息

Birkedal-Hansen H, Cobb C M, Taylor R E, Fullmer H M

出版信息

Scand J Dent Res. 1975 Sep;83(5):302-5. doi: 10.1111/j.1600-0722.1975.tb00442.x.

DOI:10.1111/j.1600-0722.1975.tb00442.x

Abstract

Latent collagenase, subject to activation by trypsin, was found in culture fluids of cells and tissues from several mammalian sources. The activation requires exposure to enzymatically active trypsin and cannot be achieved by inhibited or by heat-inactivated trypsin.

摘要

在几种哺乳动物来源的细胞和组织培养液中发现了潜在的胶原酶，该酶可被胰蛋白酶激活。这种激活需要接触具有酶活性的胰蛋白酶，而被抑制的或热灭活的胰蛋白酶无法实现激活。