罗伯特·A·古德对发现胸腺在哺乳动物免疫中的关键作用所做出的基础性贡献。
The fundamental contribution of Robert A. Good to the discovery of the crucial role of thymus in mammalian immunity.
作者信息
Ribatti Domenico
机构信息
Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy.
出版信息
Immunology. 2006 Nov;119(3):291-5. doi: 10.1111/j.1365-2567.2006.02484.x.
Abstract
Robert Alan Good was a pioneer in the field of immunodeficiency diseases. He and his colleagues defined the cellular basis and functional consequences of many of the inherited immunodeficiency diseases. His was one of the groups that discovered the pivotal role of the thymus in the immune system development and defined the separate development of the thymus-dependent and bursa-dependent lymphoid cell lineages and their responsibilities in cell-mediated and humoral immunity.
摘要
罗伯特·艾伦·古德是免疫缺陷疾病领域的先驱。他和他的同事们明确了许多遗传性免疫缺陷疾病的细胞基础和功能后果。他所在的团队是发现胸腺在免疫系统发育中的关键作用、明确胸腺依赖性和腔上囊依赖性淋巴细胞谱系的独立发育及其在细胞介导免疫和体液免疫中的作用的团队之一。
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