Donnadieu Anne Claire, Deffieux Xavier, Le Ray Camille, Mordefroid Marie, Frydman René, Fernandez Hervé
Department of Obstetrics and Gynecology, Antoine Beclere Hospital, Clamart, France.
Fertil Steril. 2006 Dec;86(6):1758-9. doi: 10.1016/j.fertnstert.2006.06.016. Epub 2006 Oct 24.
A large ovarian cyst was diagnosed at 22 weeks' of gestation in a 32-year-old woman. The ultrasonographic appearance of the ovarian cyst was unusual with multiple mobile, spherical echogenic structures floating in the cystic mass, called intracystic "fat balls." Right adnexectomy was performed by laparotomy at 28 weeks' of gestation, because of rapid growth and overall size exceeding 20 cm. Pathological examination confirmed ovarian cystic teratoma. Usually, dermoid cysts are slow-growing, even in premenopausal women. The exact mechanism related to the fast growth during pregnancy is unknown. It could be related to an unusual pattern of estrogen (E)/P receptors expression in the cystic teratoma. This case shows that a fast-growing, mature ovarian cystic teratoma may occur during pregnancy.
一名32岁女性在妊娠22周时被诊断出患有一个大的卵巢囊肿。该卵巢囊肿的超声表现不寻常，有多个可移动的球形回声结构漂浮在囊性肿物内，称为囊内“脂肪球”。由于囊肿快速生长且总体大小超过20 cm，在妊娠28周时通过剖腹术进行了右侧附件切除术。病理检查证实为卵巢囊性畸胎瘤。通常，皮样囊肿生长缓慢，即使在绝经前女性中也是如此。与孕期快速生长相关的确切机制尚不清楚。这可能与囊性畸胎瘤中雌激素（E）/孕激素（P）受体表达的异常模式有关。该病例表明，妊娠期间可能会出现快速生长的成熟卵巢囊性畸胎瘤。
