Lowery Curtis L, Eswaran Hari, Murphy Pamela, Preissl Hubert
University of Arkansas for Medical Sciences, Department of Obstetrics and Gynecology, 4301 W Markham St. Slot 518, Little Rock, AR 72205, USA.
Semin Fetal Neonatal Med. 2006 Dec;11(6):430-6. doi: 10.1016/j.siny.2006.09.002. Epub 2006 Oct 24.
The assessment of the neurological integrity of the human fetus in utero is a technically challenging problem. New brain imaging devices can substantially improve our capabilities to describe functional brain activity in the fetus. It has been well established by fetal behavioral studies and investigations in preterm and term newborns that the brain is functional in utero. The major effort required to perform effective neurological functional investigations is designation of an integrated approach to neurological assessment and the generation of normative data. Currently, it is possible to record evoked brain activity elicited by auditory and visual stimulation from the fetus. In addition, there is growing evidence that spontaneous brain activity can be recorded in the fetus. This paper explores the current status of the brain-imaging field for fetal investigations and currently available data.
评估子宫内人类胎儿的神经完整性是一个技术上具有挑战性的问题。新型脑成像设备能够大幅提升我们描述胎儿大脑功能活动的能力。胎儿行为研究以及对早产儿和足月儿的调查已充分证实,胎儿的大脑在子宫内就具备功能。进行有效的神经功能研究所需的主要工作是指定一种综合的神经评估方法并生成标准数据。目前,已能够记录胎儿对听觉和视觉刺激产生的诱发脑活动。此外,越来越多的证据表明,胎儿的自发脑活动也能够被记录。本文探讨了用于胎儿研究的脑成像领域的现状以及当前可获取的数据。