Mauri F A, Ferrero S, Barbareschi M, Scampini S, Muscarà M, Motta M, Pignataro L
Department of Morbid Anatomy and Histopathology, Ospedale SS. Trinità, Borgomanero, Italy.
Pathologica. 1990 Sep-Oct;82(1081):493-7.
Samples of normal and dysplastic laryngeal mucosa and of laryngeal epidermoid carcinomas were submitted to the AgNOR silver staining technique. AgNORs were subdivided in large (LN) and small (SN) and counted separately along their sum (TN). Overlap of values is great between normal and mildly dysplastic mucosa and between moderate and severe dysplasia. Grouping together normal with mildly dysplastic mucosa, and moderate with severe dysplasia, their mean values show minimal overlap and the differences between them are highly significant. Plotting the mean values of these two groups and of carcinomas, the linear interpolations show a clearcut increase of values.
将正常和发育异常的喉黏膜样本以及喉表皮样癌样本进行AgNOR银染色技术处理。AgNOR分为大（LN）和小（SN）两类，并分别计算其总和（TN）。正常与轻度发育异常黏膜之间以及中度与重度发育异常之间的值重叠很大。将正常与轻度发育异常黏膜归为一组，中度与重度发育异常归为一组，它们的平均值显示出最小的重叠，且两者之间的差异具有高度显著性。绘制这两组以及癌组织的平均值，线性插值显示值有明显增加。
