Legrand M, Dassonneville J C, Lesobre R
Sem Hop. 1975;51(31-34):2087-94.
Spontaneous pneumomediastinum is a relatively rare disease, the clinical signs of which may be misleading, and the physiopathology is still unknown. The authors report 7 cases collected over a period of 3 years and note the etiology, the clinical findings and the X-ray findings. The disease often affectsyoung sybjects, without any sex predominance. The initial symptom is thoracic pain and is often accompanied by dispnea. Subcutaneous emphysema only appears secondarily and may be mild. The association with pneumothorax is not rare. Among the etiological circumstances, pneumomediastinum often occurs after an effort or a respiratory infection with dyspnea. The diagnosis depends on the discovery of subcutaneous emphysema and on radiological signs in A.P. and lateral chest views. Treatment should be as conservative as possible in the usual benign forms. It should be limited to bed rest, analgesics and sedatives. In severe cases, supra-sternal drainage permits decompression of the mediastinum. The physiopathological mechanisms are discussed, but the usually accepted theory is rupture of an alveolus into the pulmonary interstitial tissue. The pressure gradient necessary for this rupture may be due to variations in alveolar or vascular pressure.
自发性纵隔气肿是一种相对罕见的疾病,其临床症状可能具有误导性,且病理生理学仍不明确。作者报告了3年内收集的7例病例,并记录了病因、临床发现和X线表现。该病常累及年轻患者,无性别差异。初始症状为胸痛,常伴有呼吸困难。皮下气肿仅继发出现,且可能较轻。与气胸的关联并不罕见。在病因方面,纵隔气肿常发生于用力或患有伴有呼吸困难的呼吸道感染之后。诊断取决于皮下气肿的发现以及前后位和侧位胸片的影像学表现。对于通常的良性形式,治疗应尽可能保守。应限于卧床休息、使用止痛剂和镇静剂。在严重病例中,胸骨上引流可使纵隔减压。文中讨论了病理生理机制,但通常被接受的理论是肺泡破裂进入肺间质组织。这种破裂所需的压力梯度可能是由于肺泡或血管压力的变化所致。