Shields Jerry A, Shields Carol L, Marr Brian P, Eagle Ralph C
Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Cornea. 2006 Aug;25(7):858-9. doi: 10.1097/01.ico.0000224641.35977.e4.
To report a case of sebaceous carcinoma of the caruncle.
A 68-year-old woman developed a slowly enlarging mass of her left caruncle. Incisional biopsy elsewhere was interpreted histopathologically as invasive squamous cell carcinoma. On the basis of the clinical findings, however, we suspected sebaceous carcinoma. Excisional biopsy with frozen section control was undertaken and the lesion was studied histopathologically.
Histopathological examination disclosed infiltration of the caruncular stroma by lobules of a malignant neoplasm that had prominent cytoplasmic vacuoles, typical of sebaceous carcinoma.
Although it is best known to arise in the meibomian glands of the tarsus, sebaceous carcinoma can rarely arise in the caruncle and can be misinterpreted histopathologically as squamous cell carcinoma.
报告一例睑裂斑皮脂腺癌病例。
一名68岁女性，其左眼睑裂斑出现一个逐渐增大的肿物。在其他地方进行的切开活检，组织病理学诊断为浸润性鳞状细胞癌。然而，根据临床表现，我们怀疑是皮脂腺癌。于是进行了切除活检并做冰冻切片检查，对病变进行了组织病理学研究。
组织病理学检查显示，一个恶性肿瘤的小叶浸润睑裂斑基质，该肿瘤具有明显的细胞质空泡，这是皮脂腺癌的典型特征。
皮脂腺癌虽然最常见于睑板的睑板腺，但很少发生于睑裂斑，并且在组织病理学上可能被误诊为鳞状细胞癌。
