Dahl Christian, Kjølhede Preben
Department of Molecular and Clinical Medicine, Division of Obstetrics and Gynecology, Linköping University Hospital, Faculty of Health Sciences, Linköping University, Linköping 58185, Sweden.
Acta Obstet Gynecol Scand. 2006;85(10):1252-8. doi: 10.1080/00016340600839890.
To determine if maternal age (35 years of age or older) in primiparous women is a risk factor for the development of obstetric anal sphincter rupture (OASR) and to identify obstetric factors associated with it.
This is a retrospective case-control study. The study population was made up of the 5,345 primiparous women aged 24-45 years who delivered vaginally with singleton live-born neonates during 1990-99 at the Department of Obstetrics and Gynecology, Linköping University Hospital, Sweden. As cases the 327 primiparous women aged 35-45 years at delivery were selected. For each case two primiparous controls ten years younger were selected, matched for gestational age and year of delivery, in all 654 controls. Maternal, obstetrical, and neonatal data were obtained from the delivery records. Obstetric factors for the development of OASR were assessed with multivariate logistic regression analysis.
No significant association was found between the primiparous age category and OASR. Vacuum extraction, forceps delivery, and the head circumference of the neonate were found to be independent risk factors for OASR, while the use of mediolateral episiotomy or epidural analgesia were independent protective factors for developing OASR.
Primiparous women, 35 years of age or older, do not seem to have a greater risk of OASR than younger primiparous women. Risk factors for OASR are instrumental vaginal delivery and the size of the neonate. Mediolateral episiotomy and epidural analgesia seem to reduce the risk for OASR.
确定初产妇年龄(35岁及以上)是否为产科肛门括约肌破裂(OASR)发生的危险因素,并识别与之相关的产科因素。
这是一项回顾性病例对照研究。研究人群由1990 - 1999年期间在瑞典林雪平大学医院妇产科经阴道分娩单胎活产新生儿的5345名24 - 45岁初产妇组成。选取327名分娩时年龄在35 - 45岁的初产妇作为病例。为每个病例选取两名年龄小十岁的初产妇作为对照,根据孕周和分娩年份进行匹配,共654名对照。从分娩记录中获取产妇、产科和新生儿数据。采用多因素逻辑回归分析评估OASR发生的产科因素。
初产妇年龄分组与OASR之间未发现显著关联。发现真空吸引助产、产钳助产和新生儿头围是OASR的独立危险因素,而会阴侧切术或硬膜外镇痛的使用是发生OASR的独立保护因素。
35岁及以上的初产妇发生OASR的风险似乎并不比年轻初产妇更高。OASR的危险因素是器械助产分娩和新生儿大小。会阴侧切术和硬膜外镇痛似乎可降低OASR的风险。