Hino Asuka, Adachi Hisashi, Enomoto Mika, Furuki Kumiko, Shigetoh Yoshiyuki, Ohtsuka Maki, Kumagae Shun-Ichi, Hirai Yuji, Jalaldin Ali, Satoh Akira, Imaizumi Tsutomu
Department of Internal Medicine, Division of Cardio-Vascular Medicine and Cardiovascular Research Institute, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, Japan.
Diabetes Res Clin Pract. 2007 Jun;76(3):383-9. doi: 10.1016/j.diabres.2006.09.033. Epub 2006 Oct 30.
In Japan, metabolic syndrome used to be rare, and the level of coffee consumption was low. However, the Japanese life style has been changing rapidly, and these changes have been associated with a steady increase in the frequency of metabolic syndrome and with greater consumption of coffee. We examined the relationship between metabolic syndrome and the consumption of coffee or green tea. A total of 1902 Japanese aged over 40 years (785 men and 1117 women) received population-based health check-up in 1999. We measured components of metabolic syndrome (blood pressure, waist circumference, fasting plasma glucose, and lipid profiles). Eating and drinking patterns were evaluated by a food frequency questionnaire. Multivariate analyses were performed to clarify the association between coffee or green tea consumption and the components of metabolic syndrome. All components of metabolic syndrome except for HDL-cholesterol were significantly (p<0.01) and inversely related to coffee but not green tea consumption by multivariate analysis after adjusting for confounding factors. The larger was the number of components of metabolic syndrome, the lower was the level of coffee consumption (p<0.0001). In addition, there was a high frequency of metabolic syndrome in small coffee drinkers. Thus, coffee but not green tea consumption was inversely associated with metabolic syndrome.
在日本,代谢综合征过去较为罕见,咖啡消费量也较低。然而,日本人的生活方式变化迅速,这些变化与代谢综合征发病率的稳步上升以及咖啡消费量的增加有关。我们研究了代谢综合征与咖啡或绿茶消费之间的关系。1999年,共有1902名40岁以上的日本人(785名男性和1117名女性)接受了基于人群的健康检查。我们测量了代谢综合征的各项指标(血压、腰围、空腹血糖和血脂谱)。通过食物频率问卷评估饮食模式。进行多变量分析以阐明咖啡或绿茶消费与代谢综合征各项指标之间的关联。在调整混杂因素后,多变量分析显示,除高密度脂蛋白胆固醇外,代谢综合征的所有指标均与咖啡消费呈显著负相关(p<0.01),而与绿茶消费无关。代谢综合征的指标数量越多,咖啡消费量越低(p<0.0001)。此外,咖啡饮用量少的人群中代谢综合征的发生率较高。因此,咖啡消费而非绿茶消费与代谢综合征呈负相关。