Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea.
Nutrients. 2018 Sep 1;10(9):1201. doi: 10.3390/nu10091201.
This study investigated the associations of green tea, coffee, and caffeine consumption with self-report lifetime depression in the Korean population using data from the Korean National Health and Nutrition Examination Survey. In total, 9576 participants (3852 men and 5724 women) aged 19 years or older were selected for the present study. Green tea, coffee, and caffeine consumption levels were assessed with a validated food frequency questionnaire. Multivariate logistic regression analysis was used to determine the odds ratios (OR) and 95% confidence intervals (CIs) for depression according to green tea, coffee, and caffeine consumption. Frequent green tea consumers (≥3 cups/week) had 21% lower prevalence of depression (OR = 0.79, 95% CI = 0.63⁻0.99, for trend = 0.0101) than green tea non-consumers after adjustment for potential confounders. Likewise, frequent coffee drinkers (≥2 cups/day) had 32% lower prevalence of depression (OR = 0.68, 95% CI = 0.55⁻0.85, for trend = 0.0026) than coffee non-drinkers after adjustment for potential confounders. Also, participants in the highest quartile of caffeine consumption had 24% lower prevalence of depression than those in the lowest quartile (OR = 0.76, 95% CI = 0.62⁻0.92, for trend = 0.0032). Frequent consumption of green tea, coffee, or caffeine was associated with a reduced prevalence of self-report lifetime depression in Korean adults. A prospective study and randomized clinical trials should be conducted to confirm the inverse relationships of green tea and coffee consumption with risk of depression.
本研究使用韩国国民健康与营养调查的数据,调查了绿茶、咖啡和咖啡因摄入与韩国人群自我报告的终身抑郁症之间的关联。总共选择了 9576 名年龄在 19 岁及以上的参与者(3852 名男性和 5724 名女性)进行本研究。使用经过验证的食物频率问卷评估绿茶、咖啡和咖啡因的摄入量。使用多变量逻辑回归分析来确定根据绿茶、咖啡和咖啡因摄入情况,抑郁的优势比(OR)和 95%置信区间(CI)。经常饮用绿茶(≥3 杯/周)的人患抑郁症的比例降低了 21%(OR=0.79,95%CI=0.63-0.99,趋势检验=0.0101),在调整了潜在混杂因素后。同样,经常喝咖啡(≥2 杯/天)的人患抑郁症的比例降低了 32%(OR=0.68,95%CI=0.55-0.85,趋势检验=0.0026),在调整了潜在混杂因素后。此外,咖啡因摄入量最高四分位数的参与者患抑郁症的比例比最低四分位数的参与者低 24%(OR=0.76,95%CI=0.62-0.92,趋势检验=0.0032)。经常饮用绿茶、咖啡或咖啡因与韩国成年人自我报告的终身抑郁症患病率降低有关。应该进行前瞻性研究和随机临床试验,以确认绿茶和咖啡摄入与抑郁风险之间的反比关系。
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