Shenderovich S F, Feklisova L V, Smirnov Iu A, Kuznetsova M A
Vopr Virusol. 1990 Nov-Dec;35(6):466-8.
Antigenic differences were found in influenza B virus variants isolated and propagated in different systems: chick embryos (E variants) and MDCK cell culture (M variants). The antigenic differences in M and E variants were detected in HI tests with polyclonal mouse sera and monoclonal antibodies as well as in biological neutralization tests in chick embryos and MDCK cell culture, and confirmed when M and E variants were used as antigens for antibody detection in human sera. By protein mobility in PAGE, M and E variants did not differ from each other and were also identical with the reference B/Victoria/87 strain.
在不同系统（鸡胚（E变异株）和MDCK细胞培养物（M变异株））中分离和繁殖的乙型流感病毒变异株中发现了抗原差异。在使用多克隆小鼠血清和单克隆抗体的血凝抑制试验以及鸡胚和MDCK细胞培养物中的生物中和试验中检测到M和E变异株的抗原差异，并且当将M和E变异株用作人血清中抗体检测的抗原时得到了证实。通过聚丙烯酰胺凝胶电泳中的蛋白质迁移率分析，M和E变异株彼此之间没有差异，并且也与参考B/维多利亚/87株相同。
